Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
| Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
| Upregulated in class | wtNotch |
| GeneSet | NCI_AURORA B SIGNALING |
| Enrichment Score (ES) | -0.7418513 |
| Normalized Enrichment Score (NES) | -1.8454754 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.08803047 |
| FWER p-Value | 0.059 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | RHOA | 580142 5900131 5340450 | 1979 | 0.998 | -0.0669 | No | ||
| 2 | RACGAP1 | 3990162 6620736 | 3408 | 0.437 | -0.1265 | No | ||
| 3 | VIM | 20431 | 4577 | 0.235 | -0.1800 | No | ||
| 4 | KIF20A | 2650050 | 5090 | 0.183 | -0.2003 | No | ||
| 5 | MYLK | 4010600 7000364 | 5581 | 0.144 | -0.2209 | No | ||
| 6 | AURKC | 4060687 | 7232 | 0.069 | -0.3070 | No | ||
| 7 | PSMA3 | 5900047 7040161 | 8176 | 0.045 | -0.3559 | No | ||
| 8 | DES | 1450341 | 8386 | 0.041 | -0.3656 | No | ||
| 9 | SGOL1 | 1980075 5220092 6020711 | 8402 | 0.040 | -0.3648 | No | ||
| 10 | CBX5 | 3830072 6290167 | 9256 | 0.024 | -0.4097 | No | ||
| 11 | NPM1 | 4730427 | 9492 | 0.020 | -0.4215 | No | ||
| 12 | BUB1 | 5390270 | 10159 | 0.009 | -0.4570 | No | ||
| 13 | KIF2C | 6940082 | 11750 | -0.018 | -0.5419 | No | ||
| 14 | KLHL13 | 6590731 | 13297 | -0.059 | -0.6227 | No | ||
| 15 | PPP1CC | 6380300 2510647 | 15240 | -0.251 | -0.7173 | No | ||
| 16 | EVI5 | 6380040 | 15696 | -0.367 | -0.7272 | Yes | ||
| 17 | AURKB | 5890739 | 15969 | -0.458 | -0.7237 | Yes | ||
| 18 | SMC4 | 5910240 | 16168 | -0.524 | -0.7136 | Yes | ||
| 19 | SMC2 | 4810133 | 16227 | -0.548 | -0.6950 | Yes | ||
| 20 | STMN1 | 1990717 | 16449 | -0.636 | -0.6817 | Yes | ||
| 21 | BIRC5 | 110408 580014 1770632 | 16722 | -0.790 | -0.6650 | Yes | ||
| 22 | CENPA | 5080154 | 16744 | -0.803 | -0.6343 | Yes | ||
| 23 | PPP2R5D | 4010156 380408 5550112 5670162 | 17034 | -0.982 | -0.6110 | Yes | ||
| 24 | INCENP | 520593 | 17229 | -1.082 | -0.5786 | Yes | ||
| 25 | AURKA | 780537 | 17299 | -1.140 | -0.5371 | Yes | ||
| 26 | CDCA8 | 2340286 6980019 | 17502 | -1.320 | -0.4957 | Yes | ||
| 27 | KIF23 | 5570112 | 17597 | -1.409 | -0.4449 | Yes | ||
| 28 | NDC80 | 4120465 | 17749 | -1.583 | -0.3903 | Yes | ||
| 29 | NCL | 2360463 4540279 | 18025 | -1.866 | -0.3312 | Yes | ||
| 30 | RASA1 | 1240315 | 18093 | -1.945 | -0.2577 | Yes | ||
| 31 | NSUN2 | 2120193 | 18099 | -1.961 | -0.1803 | Yes | ||
| 32 | CUL3 | 1850520 | 18170 | -2.066 | -0.1022 | Yes | ||
| 33 | NCAPH | 6220435 | 18560 | -3.183 | 0.0030 | Yes |
